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This means they may find it difficult to manage their use of cocaine and may experience addiction in the most severe cases of SUD. Using cocaine can cause changes to the brain, such as in the reward system, resulting in a buildup of dopamine and making it difficult for someone to stop using the substance. […]

Mixing cocaine with other substances, such as heroin or alcohol, can also be life threatening. If a heart attack occurs after taking cocaine, a person may experience discomfort or tightness in the center or left side of their chest. This typically lasts for several minutes, or may go away and return, or may last for

Taking these products isn’t an efficient technique for eradicating cocaine out of your system. Along with the physical risks, cocaine use can affect your life in other ways. As brain functions deteriorate from ongoing cocaine use, a person may start to develop psychotic symptoms, such as hallucinations and losing touch with reality. We and our

Mescaline tells less of a story about the drug itself than it does about the people who harvested, used, abused, regulated and investigated it. But, Jay explains, mescaline’s role in inducing a quasi-psychosis “pushed its subjective effects to the margins.” Eventually, mescaline was relegated to the “recreational drug” bin, along with LSD, MDMA (“ecstasy”), psilocybin,

If a person uses cocaine regularly for a long period, their brain may develop a tolerance to the drug. Prolonged use of cocaine may interfere with this natural process, resulting in a buildup of dopamine that can make the drug seem even more desirable. However, 2020 research on monkeys suggests that another neurotransmitter called glutamate